Fetal Lung Volume and Pulmonary Artery Resistance Index Measurement in Term Diabetic Pregnancy and Their Correlation With Neonatal Outcome: a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 主要终点
- neonatal respiratory distress
研究概览
简要总结
The aim of this study is to determine cut-off values for fetal lung volume by VOCAL and pulmonary artery resistance index by pulsed Doppler in fetuses of diabetic mothers, and correlate the results with postnatal respiratory distress of the term neonates.
详细描述
Research question:
Can the assessment of fetal lung volume by Virtual Organ Computed-aided Analysis (VOCAL) and pulmonary artery resistance index by pulsed Doppler predict neonatal respiratory distress syndrome in term fetuses of diabetic mothers?
Research hypothesis:
The assessment of fetal lung volume by VOCAL and pulmonary artery resistance index by pulsed Doppler can predict neonatal respiratory distress syndrome in term fetuses of diabetic mothers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Diabetic pregnant women 38 weeks gestation admitted for elective termination due to various obstetric indications
排除标准
- •Pregnancy complicated by medical disorders other than Diabetes Mellitus (hypertension, pre-eclampsia, cardiac disorders, thyroid disorders, anemia with pregnancy...etc).
- •Autoimmune disorders.
- •Congenital fetal anomalies.
- •Macrosomia and intrauterine growth restriction (IUGR).
- •Intrauterine fetal death (IUFD).
- •Amniotic fluid index <5cm or >20cm.
- •Patients taking steroids within one week of measurement of lung volume.
结局指标
主要结局
neonatal respiratory distress
时间窗: immediately after delivery
Occurrence of neonatal respiratory distress immediately after delivery utilizing APGAR score at birth in numbers
次要结局
- • Neonatal mortality rate(One week after delivery)
研究者
dr mohamed laban
Professor Mohamed Laban
Ain Shams University