The efficacy and safety of Kampo (Japanese herbal) medicines, maoto and maotokasekko, in treatment of influenza virus infections
Phase 4
- Conditions
- influenza virus infections
- Registration Number
- JPRN-UMIN000000848
- Lead Sponsor
- Oriental Medicine Research Center, Kitasato University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Not provided
Exclusion Criteria
1. patients who is taking any Kampo medicines 2. patients who took any Kampo medicines in the past 4 weeks 3. patients who need to start taking other medicines simultaneously 4. patients with active cardiovascular diseases 5. patients with active hyperthyroidism 6. patients in danger of urinary retention 7. patients with severe delicate constitution 8. patients with hypokalemia 9. patients with significant liver or renal dysfunction 10. patients with allergic reaction to the test drugs 11. patients with some disease which may deteriorate their performance status such as cancer or heart failure 12. patients considered inappropriate for this trial by the physicians-in-charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method time to the alleviation of all major symptoms definition of "alleviation of all major symptoms" 1. without sensation of heat 2. oral temperature is 37.8 degree C or lower 3. disappearance or mild state of all the symptoms below 1. sore throat 2. cough 3. muscle pain 4. headache 4. above state is kept more than 24 hours
- Secondary Outcome Measures
Name Time Method time to the absence of fever time to the alleviation of individual symptoms time to the resumption of normal activities adverse drug events