Effect of Vitamin A Supplementation on Iron Metabolic Homeostasis of Preschool Children in Sichuan,China

Not Applicable

Completed

• Conditions: Iron Metabolic Homeostasis
• Interventions: Drug: iron and vitamin a

• Registration Number: NCT01355263
• Lead Sponsor: Chengdu Maternal and Children's Health Care Hospital

Brief Summary

The investigators plan to perform a randomized, mutual-control and double-blinded cohort study to further exploit the vitamin A supplementation on iron metabolic homeostasis (including iron reserve, mobilization and absorption status in the same population) compared with solely iron and vitamin A plus iron.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-05-09
• Study First Submitted QC: 2011-05-17
• Study First Posted: 2011-05-18
• Study Start: 2011-07
• Primary Completion: 2012-02
• Study Completion: 2012-08
• Status Verified: 2013-02
• Last Update Submitted: 2013-02-18
• Last Update Posted: 2013-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 450

Inclusion Criteria

• apparent health;
• Hb concentration>60 g/L;
• C-reaction protein (CRP)<10 mg/L;
• parental or guardian approval of participation in all aspects of the study; and
• parental/guardian agreement to avoid the additional use of vitamin and mineral supplements during the investigation.

Exclusion Criteria

• does not match the inclusion criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
iron tablet, vitamin a capsule	iron and vitamin a	children in Group I received a 200,000 IU vitamin A capsule just one time initially; Group II received ferrous sulfate (element Fe 1-2 mg/kg•day) once a day for 6 months;.

Primary Outcome Measures

Name	Time	Method
hemoglobin	six months