Correlation of Right-left Shunt Detection in Cardioembolism Etiology in Stroke Patient.

Completed

• Conditions: Foramen Ovale Patent

• Registration Number: NCT02351076
• Lead Sponsor: University Hospital Ostrava

Brief Summary

The aim of the study is to compare correlation for right to left shunts (mainly patent foramen ovale) detection for three methods-transesophageal echo as a gold standard, transcranial doppler with contrast agent (microbubbles) and new method- Flow detection system ( Cardiox TM) in young stoke patients ( age under 55 years).

Detailed Description

The aim of the study is to compare correlation for right to left shunts (mainly patent foramen ovale) detection for three methods-transesophageal echo as a gold standard, transcranial doppler with contrast agent (microbubbles) and new method- Flow detection system ( Cardiox TM) in young stoke patients ( age under 55 years). Flow detection systém is a new method for right to left shunt detection comfortable for patients, not dependent on experienced examinator and only one method with exact valsalve maneuver measurement. Right to left shunt could be important etiology of cardioembolization in young stroke patient population, therefore screening for this condition is recommended in all young patient after ischemic stroke especially with unclear etiology. Flow detection systes seams to be ideal screening method for this patients.

Study Timeline

• Study Start: 2014-08
• Study First Submitted: 2014-11-23
• Study First Submitted QC: 2015-01-26
• Study First Posted: 2015-01-30
• Primary Completion: 2016-06
• Study Completion: 2016-08
• Status Verified: 2016-09
• Last Update Submitted: 2016-09-07
• Last Update Posted: 2016-09-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

ischemic stroke / TIA, signed informed consent -

Exclusion Criteria

imposibillity to undergo transesophageal echo, transcranial doppler with contrast or Cardiox flow detection system

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
detection of right-to-left shunt	1 week	Correletation of right-to-left shunt detection by 3 methods: transesophageal echocardiography, transcranial Doppler with contrast agent (microbubbles) and Flow detection system (Cardiox TM)

Trial Locations

Locations (1)

University Hospital Ostrava; 🇨🇿 Ostrava, Czech Republic