Comparison of Two Different Measurement of Endotracheal Tube Cuff Pressure for Ventilatory Associated Pnemonia in Severe Brain Injured Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Duration
研究概览
简要总结
The effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia.
详细描述
Aim of this study is to evaluate the effect of endotracheal cuff pressure measurement technique for preventing ventilatory associated pneumonia of severe traumatic brain injured patients in a tertiary level intensive care unit.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ASA classification of 1 - 2- 3 patients Patients required mechanical ventilation support for more than 48 hours Patients diagnosed with Traumatic brain injury
排除标准
- •Official patient relatives who rejected to give informed consent for the study Patients diagnosed with aspiration pneumonia during ICU follow up Patients diagnosed with Acute Respiratory Distress Syndrome Patients diagnosed with cavitary lung lesion Primary lung cancer Metastatic lung cancer Congenitally immune deficiency Leukopenia Neutropenia Tracheostomized patients Post cardiopulmonary arrest patients Pregnancy
结局指标
主要结局
Duration
时间窗: 30 days
Follow up duration in ICU
Score
时间窗: 48.hour - 72.hour - 96.hour
Clinical Pulmonary Infection Score Change from baseline at 48.hour, 72.hour and 96.hour
CRP
时间窗: 48.hour - 72.hour - 96.hour
C Reactive Protein measurement change from Baseline at 48.hour, 72.hour and 96.hour
Oxygenation
时间窗: 48.hour - 72.hour - 96.hour
Fractional Inspiratory Oxygen levels change from baseline at 48.hour, 72.hour and 96.hour
PEEP
时间窗: 48.hour - 72.hour - 96.hour
Positive End Expiratory Pressure levels change from baseline at 48.hour, 72.hour and 96.hour during ventilatory support
Ventilation
时间窗: 30 days
Mechanically ventilated period
次要结局
- Tracheal aspirate(0.hour - 48.hour - 72.hour - 96.hour)
- Mortality(30 days)
- Bacterial distribution(0.hour - 48.hour - 72.hour - 96.hour)