Hospital-based case control study to assess vaccine effectiveness against Novel Influenza A (H1N1) and occurance of severe acute respiratory infections (SARI) in adults between 18 and 65 years of age in Berlin, 2009-10 - Influenza-Impfeffektivitätsstudie (IIE-Studie)

Robert Koch-Institut, Abteilung für Infektionsepidemiologie0 sites478 target enrollmentDecember 9, 2009

Overview

No summary available.

Registry

who.int

Start Date

December 9, 2009

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

All

Sponsor

Robert Koch-Institut, Abteilung für Infektionsepidemiologie

•A resident of Berlin,
•a) who is hospitalized in one of the participating clinics of the Vivantes network, AND
•b) who is between 18 and 65 years old, AND
•c) who gave written informed consent to participate in the study, AND
•d) who is hospitalized due to an acute respiratory illness, defined as presence of the following symptoms in the past 10 days
•\- at least one systemic symptom: fever, or chills, or musclepain, or headache, AND
•\- at least one respiratory symptom: cough or sore throat
•\- a suspected diagnosis of influenza, acute bronchitis, or pneumonia assessed by a medical doctor

•a) who can not give written informed consent
•b) who have insufficient capability to communicate for medical reasons like aphasia or unconsciousness
•c) who live in a nursing home
•d) who have a history of severe anaphlaxis after vaccination
•e) who already had 14 days or earlier before hospitalization the diagnosis of 2009 Novel Influenza confirmed by PCR