Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models: Testing Speech-Based Machine Learning Algorithms for Clinical Assessment and Risk Stratification in Mental Health Presentations
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- Clinical diagnosis
研究概览
简要总结
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, bipolar disorder, generalized anxiety disorder, major depressive disorder, obsessive compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and schizophrenia. We aim to develop tools that can support clinicians in making more accurate and efficient diagnoses.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 13 Years 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Clinical diagnosis
时间窗: 0 months, 3 months, 6 months
Clinician diagnosis will be recorded for each participant at first assessment, 3-month, and 6-month follow-up. Diagnoses will be made according to ICD-11 or DSM-5 criteria for the compatible disorders: ADHD, ASD, BPAD, GAD, MDD, OCD, PTSD, and SSD. Additional relevant labels such as other mental health disorders, clinical high risk (CHR) and substance use may be recorded.
Performance of AI models
时间窗: 0 months, 3 months, 6 months
The performance of the Mercuria and Solicue AI models will be evaluated using performance metrics of accuracy, balanced accuracy, sensitivity (recall), specificity, positive predictive value (precision), negative predictive value, F1 score, AUC-ROC. Predicted labels will be compared with the ground truth clinical diagnoses obtained from the participating mental health clinics. Confidence acceptance threshold will be set.
Speech Battery ("PSY-10") audio
时间窗: At initial assessment
The speech battery consists of prompt-based tasks designed to elicit speech responses from participants in the form of monologues. This includes text reading, recall, and picture description tasks.
次要结局
- Mood Disorder Questionnaire (MDQ)(At initial assessment)
- Patient Health Questionnaire-9 (PHQ-9)(At initial assessment)
- DSM-5 Level 1 Cross-Cutting Symptom Measure (DSM-XC)(At initial assessment)
- Reported Distress(After initial assessment)