The Relationship Between Intraoperative ETCO2 Levels and Postoperative Pain and Nausea-Vomiting in Laparoscopic Robotic Prostatectomy Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain, Postoperative
- Sponsor
- Ankara Etlik City Hospital
- Enrollment
- 109
- Locations
- 1
- Primary Endpoint
- Postoperative nausea and vomiting (PONV) Score
- Status
- Completed
- Last Updated
- 12 months ago
Overview
Brief Summary
The aim of our study is to investigate the relationship between intraoperative ETCO2 levels and postoperative nausea-vomiting and pain scores in patients undergoing robotic laparoscopic radical prostatectomy. The investigators will monitor patients' 24-hour postoperative pain, nausea-vomiting and the consumption of additional analgesic and antiemetic medications.
Detailed Description
Robotic surgery provides several advantages in the field of surgery, including a three-dimensional view of the surgical site, the elimination of surgeon hand tremors, and enhanced precision in movements. Additionally, it offers benefits such as reduced intraoperative bleeding, faster return to daily functions for patients, and decreased hospitalization duration. Consequently, the use of robots in various surgical procedures has become widespread in contemporary medical practice. Robot-assisted laparoscopic radical prostatectomy is a surgical technique performed in a head-down Trendelenburg position with intraperitoneal insufflation of carbon dioxide (CO2). This positioning and pneumoperitoneum lead to an increase in intraabdominal pressure, as well as elevated intracranial and intraocular pressures. End-tidal carbon dioxide (ETCO2) levels can vary during laparoscopic surgery. An increase in ETCO2 levels has been reported to cause an elevation in intracranial pressure, leading to an increased incidence of postoperative nausea and vomiting. Some studies in the literature have investigated the relationship between ETCO2 values and the incidence of postoperative nausea and vomiting in patients. Furthermore, it is believed that hypercarbia (elevated carbon dioxide levels) may have an impact on postoperative pain. The aim of our study is to investigate the relationship between intraoperative ETCO2 levels and postoperative nausea, vomiting, and pain scores in patients undergoing robotic laparoscopic radical prostatectomy. The investigators will monitor patients' 24-hour postoperative pain, nausea, vomiting, and the consumption of additional analgesic and antiemetic medications.
Investigators
Yusuf Özgüner
Principal Investigator
Ankara Etlik City Hospital
Eligibility Criteria
Inclusion Criteria
- •Individuals between the ages of 18 and
- •Patients with American Society of Anesthesiologists (ASA) scores I, II, or III.
- •Patients who have undergone robotic laparoscopic prostatectomy in the operating room.
Exclusion Criteria
- •Patients under 18 years old or over 80 years old.
- •Patients with American Society of Anesthesiologists (ASA) scores IV and above.
- •Patients who refuse to participate in the study.
- •Patients undergoing emergency surgery.
Outcomes
Primary Outcomes
Postoperative nausea and vomiting (PONV) Score
Time Frame: 0-2-4-8-12-24 hours postoperatively
Postoperative nausea and vomiting recording in patients. * 0=no PONV: patient reports no nausea and has had no emesis episodes; * 1=mild PONV: patient reports nausea but declines antiemetic treatment; * 2=moderate PONV: patient reports nausea and accepts antiemetic treatment; and * 3=severe PONV: nausea with any emesis episode (retching or vomiting). Higher scores indicate severe postoperative nausea and vomitting.
Secondary Outcomes
- Pain on the Numeric Rating Scale (NRS)(0-2-4-8-12-24 hours postoperatively)