Studies to gain insight how the drugs PCSK9-inhibitors and statins affect cholesterol and bile acid metabolism

Phase 1

• Conditions: Healthy volunteers; Therapeutic area: Phenomena and Processes [G] - Metabolism [G03]

• Registration Number: CTIS2023-505726-34-02
• Lead Sponsor: Karolinska University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-31
• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Male
• Target Recruitment: 8

Inclusion Criteria

18-64 year old, Male

Exclusion Criteria

Cardiovascular disease, Any chronic medication use, Steroid treatment for the last six months or HRT, Coagulopathy, Musculoskeletal or neurologic disease, Inclusion in any other concurrent medical research study, Cerebrovascular disease (e.g. stroke, prior aneurysm), Pulmonary disease (e.g. pulmonary hypertension, COPD), Metabolic disease (incl. but not limited to Cushing disease, Diabetes), Renal disease (by CKD criteria), Active inflammatory bowel syndrome, Cancer, Pregnancy, Smoker

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified