Use of N-Butyl Cyanoacrylate in Transarterial Emergency Embolization

Completed

• Conditions: Haemostasis Embolisation
• Interventions: Other: Clinical data; Other: Imaging data; Other: Biological data

• Registration Number: NCT06301919
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

NBCA is a synthetic biodegradable cyanoacrylate basis glue, modified by the addition of a monomer with adhesive, hemostatic, and antiseptic properties.

Its use requires a steep learning curve to control emulsification of the NBCA/lipiodol mixture, and injection, to avoid non-target embolization.

The aim of this retrospective monocentric study was to evaluate safety and efficacy of use of NBCA as embolic agent in emergency setting.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-03
• Study Start: 2024-03-01
• Study First Submitted: 2024-03-04
• Study First Submitted QC: 2024-03-04
• Study First Posted: 2024-03-08
• Primary Completion: 2024-05-01
• Study Completion: 2024-05-01
• Last Update Submitted: 2025-01-24
• Last Update Posted: 2025-01-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

• All patients referred to our hospital and treated by TAE with NBCA, based on clinical decisions in emergency and CT scan.

Exclusion Criteria

• Patients lost for follow-up, patients without preoperative CT.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Included patients	Clinical data	All patients referred to our hospital and treated by TAE with NBCA, based on clinical decisions in emergency and CT scan.
Included patients	Imaging data	All patients referred to our hospital and treated by TAE with NBCA, based on clinical decisions in emergency and CT scan.
Included patients	Biological data	All patients referred to our hospital and treated by TAE with NBCA, based on clinical decisions in emergency and CT scan.

Primary Outcome Measures

Name	Time	Method
Evaluation of technical success	Month : 1	Analysis of angiographic results.

Secondary Outcome Measures

Name	Time	Method
Assessment of clinical success	Month : 1	Absence of death due to massive blood loss

Trial Locations

Locations (1)

CHU de Saint-Etienne; 🇫🇷 Saint-Priest-en-Jarez, France