Psychological Prevention of Relapse in Psychosis
- Conditions
- PsychosisMental and Behavioural Disorders
- Registration Number
- ISRCTN83557988
- Lead Sponsor
- King's College London (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 301
Participants are recruited from identified psychiatric teams in four NHS Trusts.
Entry criteria:
1. Current diagnosis of psychosis
2. Non-affective (International Statistical Classification of Diseases and Related Health Problems, Tenth edition [ICD-10], F20)
3. Aged 18 to 65 years, either sex
4. Second or subsequent episode, which started not more than three months before entry
5. Rated at least four (moderate severity) on the Positive and Negative Syndrome Scale (PANSS) on at least one positive psychotic symptom
Added 03/03/2009:
1. Primary diagnosis of alcohol or substance dependency, organic syndrome or learning disability
2. Inadequate command of English to engage in psychological therapy
3. Unstable residential arrangements and so unlikely to be available for therapy and/or assessments over period of trial
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relapse and days in hospital over 24 months.
- Secondary Outcome Measures
Name Time Method 1. Pattern of symptom change (PANSS total scores and subscale scores, Psychotic SYmptom RATing Scales [PSYRATS], Beck Depression Inventory [BDI], Beck Anxiety Inventory [BAI]) over 12 and 24 months<br>2. Social functioning (time budget) at 24 months