NCT02063919已完成不适用
Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome
Shandong University1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2013年11月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- The operational taxonomy unit in the colorectal mucosal microbiome.
研究概览
简要总结
The purpose of this study is to determine whether an association between endomicroscopic pattern and colorectal mucosal microbiome exists.
详细描述
The gut microbiome plays a pivotal role in the intestinal pathophysiology. The mucosal microbiome is in the front face of microbiome-host cross-talk. Confocal laser endomicroscopy (CLE) can provide realtime mucosal images during ongoing endoscopy. We hypothesized that the mucosal pattern, here evaluated by endomicroscopy, may constitute specific microbiome niches and participate the evolvement of the mucosal microbiome.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years old ≤ age < 80 years old
- •Scheduled for colonoscopy in Qilu Hospital
排除标准
- •antibiotic usage within 2 months
- •probiotic or prebiotic usage within 2 months
- •liver cirrhosis
- •impaired renal function
- •coagulopathy
- •pregnancy
- •breastfeeding
- •inability to provide informed consent
- •known allergy to fluorescein sodium
结局指标
主要结局
The operational taxonomy unit in the colorectal mucosal microbiome.
时间窗: 6 months
次要结局
未报告次要终点
研究者
Yanqing Li
Vice president of Qilu Hospital
Shandong University
研究点 (1)
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