Study of the Loss of AV Synchrony at Maximum Exercise

Terminated

• Conditions: Pacemaker; Exercise; Blood Pressure
• Interventions: Other: Stress Test

• Registration Number: NCT03859167
• Lead Sponsor: Vanderbilt University Medical Center

Brief Summary

Investigators will identify a group of patients with complete heart block and a dual chamber pacemaker who will be expected to be able to exercise on a treadmill. Investigators will utilize symptom logs, cuff and continuous blood pressure monitoring. It is planned to study the symptomatic impact of loss of AV synchrony at significant levels of exercise.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2019-02-27
• Study First Submitted QC: 2019-02-27
• Study First Posted: 2019-03-01
• Study Start: 2019-09-10
• Status Verified: 2023-04
• Primary Completion: 2023-04-10
• Study Completion: 2023-04-10
• Last Update Submitted: 2023-04-11
• Last Update Posted: 2023-04-14

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• Complete AV Block
• Age less than 60
• Easily programmable dual chamber pacemaker

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Exclusion Criteria

• Age > 60
• Significant Heart Failure
• Significant angina
• History of claudication
• Significant orthopedic issues
• Evidence of sinus node dysfunction
• Taking beta blockers or non-dihydropyridine calcium channel blockers

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Participants with AV block with pacemaker	Stress Test	Participants will have a stress test, and results will be collected and recorded.

Primary Outcome Measures

Name	Time	Method
The number of participants with Loss of AV synchrony at maximum exercise	Baseline to end of stress test approximately 60 minutes.

Trial Locations

Locations (1)

Vanderbilt University Medical Center; 🇺🇸 Nashville, Tennessee, United States