Effect of Shufeiya Prescription on Pulmonary Artery Systolic Pressure and Quality of Life in Patients with Pulmonary Hypertensio

Phase 1

Recruiting

• Conditions: Pulmonary Hypertension

• Registration Number: ITMCTR2100004860
• Lead Sponsor: The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1.Aged 18 to 80 years, gender is not limited;
2.Meets the diagnostic standard of pulmonary hypertension;
3.Patients with fixed dose and type of conventional medicine last month;
4.Patients who did not receive targeted drug therapy or targeted drug therapy regimen fixed for at least a month;
5.Patients who had not received interventional or surgical treatment within 6 months before the trial;
6.Volunteer to participate in the clinical trial, understand and sign the informed consent.

Exclusion Criteria

1.Patients with acute exacerbation of chronic heart failure, acute myocardial infarction, coronary revascularization, and cardiac resynchronization within a month before the trial;
2.Patients with acute exacerbation of COPD/combined pulmonary infection within a month before the trial;
3.Patients with right ventricular outflow tract obstruction;
4.Patients with malignant tumors, mental disorders, malignant arrhythmias and other serious diseases;
5.Patients with severe renal disease (serum creatinine > 450umol/L) or liver disease (including serum transaminase >3 times the upper limit of normal value);
6.Patients who had taken Chinese medicine preparations (including TCM decoction pieces, granules, Proprietary Chinese medicine, TCM intravenous preparations, etc.) within 2 weeks before the trial;
7.Patients with disadvantageous activities of lower limbs and unable to cooperate with the completion of relevant examinations;
8.Pregnant women and lactating women;
9.Patients with known allergy to the drug ingredients and excipients in this trial.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulmonary artery systolic pressure;

Secondary Outcome Measures

Name	Time	Method
ltrasonic cardiogram;Six minutes walking distance;Endothelin - 1;WHO functional class;Quality of Life Scale;Nitric oxide;Borg dyspnea scores;