CTRI/2026/01/102270尚未招募不适用
Identification and quantification of circulating myeloid derived suppressor cells in myeloid malignancies
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Primary outcome-proportion of circulating MDSCs. In patients of myeloid malignancies by flow cytometry
研究概览
简要总结
The goal is to identify and quantify specific mdsc populations in myeloid malignancies
Total of 40 cases comprising of 20 normal controls and 20 cases of myeloid malignancies of ages 18 and above of both genders will be enrolled
.their peripheral blood sample will be taken with consent and further flow cytometry will be done on these samples with a specicf panel for identifying the specific mdsc population. The data obtained will be analysed using statistical analytics tools such as SPSS software 25
And the result will be compiled and any association will be identified
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •newly diagnosed cases of myeloid malignancies in male or female patients more that or equal to 18 years of age For control.
- •healthy controls equal to above 18 years of age.
排除标准
- •patients on treatment for myeloid malignancies.
结局指标
主要结局
Primary outcome-proportion of circulating MDSCs. In patients of myeloid malignancies by flow cytometry
时间窗: Baseline
次要结局
- Secondary outcome - quantification of circulating PMN -MDSCs ,Mo-MDSCsand e - MDSCs in patients of myeloid malignancies and healthy controls(Association of circulating PMN-MDSCs ,Mo-MDSCs and e-MDSCs with clinicopathological parameters in myeloid malignancies)
研究者
Dr Kritika upadhyay
Maulana Azad Medical College
研究点 (1)
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