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临床试验/NCT03713788
NCT03713788已完成不适用

Muscle Stretching - the Potential Role of Endogenous Pain Inhibitory Modulation on Stretch Tolerance

University College of Northern Denmark2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2016年5月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
34
试验地点
2
主要终点
Knee extension range of motion

研究概览

简要总结

This study investigates the influence of a remote, painful stimulus on stretch tolerance. Half of the participants will receive a conditioning painful stimulus following static stretching while the other half will rest quietly.

详细描述

The effect of stretching on joint range of motion is primarily related to changes in the tolerance to stretch, but the mechanisms underlying this change are still largely unknown.

The nervous system has an inbuilt ability to modulate the perceived magnitude of afferent noxious stimuli via supraspinally mediated endogenous pain inhibition or facilitation and by engaging endogenous mechanisms pain tolerance in healthy individuals is known to increase. Thus increasing the tolerance to pain could potentially increase range of motion following stretching.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Eligibility for participation included the absence of any pain or other conditions that might affect the somatosensory system.

排除标准

  • Substance abuse,
  • History of neurological or mental disabilities
  • Lack of ability to comply with instructions
  • Delayed onset of muscle soreness.

研究组 & 干预措施

Experimental pain group

Experimental

subjects in the pain group were instructed to immerse their non-dominant hand into a container with circulating water at 1˚C to 4˚C and keep it there for 2 minutes. They were instructed to immerse it to wrist-level and keep the hand open.

干预措施: Cold pressor test (Other)

Control group

No Intervention

Participants rested in a seated position for 5 minutes.

结局指标

主要结局

Knee extension range of motion

时间窗: Passive knee extension range of motion was measured at baseline

Passively induced knee extension range of motion was measured usind the Biodex system 4 pro isokinetic dynomometer

Change in knee extension range of motion between baseline and post stretch.

时间窗: Changes in passive knee extension range of motion were measured 5 minutes after baseline measures following stretching

Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer

Changes in knee extension range of motion between post stretch and post pain.

时间窗: Changes in passive knee extension range of motion were measured 5 minutes after post stretch measures following intervention.

Changes in passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynomometer

次要结局

  • Surface electromyography measures of muscle activity(Muscle activity during the passive knee extension motion was measured at baseline)
  • Changes in surface electromyography measures of muscle activity between baseline and post stretch measures.(Changes in muscle activity during the passive knee extension motion were measured 5 minutes after baseline measures following stretching.)
  • Changes in surface electromyography measures of muscle activity between post stretch and post pain measures.(Changes in muscle activity during the passive knee extension motion were measured 5 minutes after post stretch measures following intervention.)
  • Passive resistive torque using the Biodes system 4 pro.(Passive resistive torque during the passive knee extension motion was measured at baseline.)
  • Changes in passive resistive torque measured using the Biodex system 4 pro between baseline and post stretch measures.(Changes in passive resistive torque during the passive knee extension motion was measured 5 minutes after baseline measures following stretching.)
  • Changes in passive resistive torque measured using the Biodex system 4 pro between post stretch and post pain measures.(Passive resistive torque during the passive knee extension motion was measured 5 minutes after post stretch measures following intervention.)

研究者

发起方
University College of Northern Denmark
申办方类型
Other
责任方
Principal Investigator
主要研究者

Morten Pallisgaard

Senior associate lecturer

University College of Northern Denmark

研究点 (2)

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