Cortical reorganization underlying motor recovery after low-frequency repetitive transcranial magnetic stimulation combined with occupational therapy in chronic stroke
Not Applicable
- Conditions
- Stroke
- Registration Number
- JPRN-UMIN000046520
- Lead Sponsor
- Kakeyu Hospital
- Brief Summary
After the treatment, the motor function test scores of FMA and WMFT improved significantly. The LI during movements of the affected hand increased significantly, suggesting changes in the activation balance within the primary motor, primary lesioned hemisphere. Moreover, the LI changes in the aforementioned areas significantly correlated with gains in the WMFT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) cognitive deficits (Mini-Mental State Examination score <= 23). 2) active systemic or mental illness requiring medical management. 3) seizure. 4) pathological conditions known to be contraindications for rTMS in the guidelines suggested by Wassermann (1998).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in neural activation patterns assessed with fMRI before and after therapy
- Secondary Outcome Measures
Name Time Method Fugl-Meyer Assessment Wolf Motor Function Test Action Research Arm Test Motor Activity Log