Benefits of Topical insulin in diabetic foot ulcer: Study in Tertiary Care centre of Southern Odisha
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Early granulation
研究概览
简要总结
Diabetes and its complications have been in increasing trend owing to the lifestyle changes and awareness. The cases of Diabetic foot disease are equally increasing. Diabetic foot is a debilitating condition affecting the quality of life of an individual. Thus novel clinical interventions in aiding to the early recovery of this debilitating condition is the need of hour.The complications of diabetics have been attributed to the local tissue hyperglycemia leading to micro and macrovascular changes.This trial aims to determine the benefits of topical application of insulin in dressing of diabetic foot ulcer as compared to traditional normal saline dressingin terms of speed of recovery, early granulation, graft uptake and hospital stay.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, fixed
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Diabetic foot ulcer.
排除标准
- •Active Osteomyelitis HIV/ HBsAg positive Denied consent Severe anemia Occlusion of major vessel of leg.
结局指标
主要结局
Early granulation
时间窗: 0 7, 15 days
Complete primary healing
时间窗: 0 7, 15 days
次要结局
- Better graft uptake(Low infection rate)
