Skip to main content
Clinical Trials/NCT05082922
NCT05082922
Active, Not Recruiting
N/A

Implementation of a Transdiagnostic Emotion-focused Treatment for Comorbid Emotional Problems and Chronic Pain in Clinical Care. A Sequential Replicated and Randomized Single Case Experimental Design (SCED).

Örebro University, Sweden1 site in 1 country50 target enrollmentOctober 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Emotional Problem
Sponsor
Örebro University, Sweden
Enrollment
50
Locations
1
Primary Endpoint
Patient Health Questionnaire (PHQ-9) change
Status
Active, Not Recruiting
Last Updated
2 years ago

Overview

Brief Summary

In society today, mental health problems, specifically stress-, anxiety- and depressive disorders, are a primary cause of long-term sick leave, leading to significant societal costs and suffering. One important issue hindering implementation of successful treatments is that there is a marked co-occurrence between these problems and somatic health problems, such as different types of pain. An important key to solving this problem is to develop a more integrated conceptualization of, and treatment model for, these patients' health problems. Specifically, one way to understand the co-occurrence between mental and somatic health problems is offered by the 'transdiagnostic' perspective. The aim of this project is to implement and evaluate the effectiveness of a transdiagnostic emotion-focused treatment protocol in clinical context. The treatment addresses comorbid mental (stress, anxiety- and depressive) and somatic health (pain) problems and targets core emotion regulation processes that are hypothesized to maintain and exacerbate these problems.

Registry
clinicaltrials.gov
Start Date
October 1, 2021
End Date
December 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Örebro University, Sweden
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • \> 11 points on the anxiety or depression subscale, Hospital Anxiety and Depression scale
  • somatic health problems (pain \> 3 months) with functional impairment (\>3 on question 2 of the Multidimensional Pain Inventory, MPI, OR \> 20 points on question 21-24 of the Örebro Musculoskeletal Pain Questionnaire, ÖMPQ)

Exclusion Criteria

  • severe psychiatric problems requiring immediate other treatment
  • current psychological treatment
  • recently started psychopharmacological treatment for anxiety or depression (\<3 months prior to planned treatment)
  • insufficient mastery of the Swedish language

Outcomes

Primary Outcomes

Patient Health Questionnaire (PHQ-9) change

Time Frame: repeated weekly through phase A (randomly assigned to be 4, 5 or 6 weeks) and treatment phase B (14 to 16 weeks). Total time frame of assessment is 20 weeks.

change in self rated depression. Scale range 0-27 (higher values worse outcome)

Pain change

Time Frame: repeated weekly through phase A (randomly assigned to be 4, 5 or 6 weeks) and treatment phase B (14 to 16 weeks). Total time frame of assessment is 20 weeks.

change in pain intensity (scale 0-6) and interference. Scale range 0-6 (higher values worse outcome)

Generalised Anxiety Disorder (GAD-7) change

Time Frame: repeated weekly through phase A (randomly assigned to be 4, 5 or 6 weeks) and treatment phase B (14 to 16 weeks). Total time frame of assessment is 20 weeks.

change in self rated anxiety. Scale range 0-27 (higher values worse outcome)

Symptom Catastrophizing Scale (SCS) change

Time Frame: Baseline, 5 months and 11 months as well as repeated weekly through phase A (randomly assigned to be 4, 5 or 6 weeks) and treatment phase B (14 to 16 weeks). Total time frame of assessment is 20 weeks.

Change in catastrophic interpretation of symptoms. Scale range 0-14 (higher values worse outcome)

Pain coping change

Time Frame: repeated weekly through phase A (randomly assigned to be 4, 5 or 6 weeks) and treatment phase B (14 to 16 weeks). Total time frame of assessment is 20 weeks.

change in pain worry (scale 0-6) and avoidance (scale range 0-8) (higher values worse outcome)

Secondary Outcomes

  • Psychological Inflexibility in Pain Scale (PIPS) change(Baseline, 5 months and 11 months)
  • Mini international neuropsychiatric interview (MINI)(Baseline, 5 months)
  • EQ5-D change(Baseline, 5 months and 11 months)
  • Montgomery Åsberg Depression Rating Scale (MADRS) change(Baseline, 5 months and 11 months)
  • Difficulties in Emotion Regulation Scale (DERS-16) change(Baseline, 5 months and 11 months)
  • Work limitation questionnaire-16 change(Baseline, 5 months and 11 months)
  • Multidimensional Pain Inventory (MPI) change(Baseline, 5 months and 11 months)
  • Insomnia Sleep Inventory (ISI) change(Baseline, 5 months and 11 months)

Study Sites (1)

Loading locations...

Similar Trials