Evaluation of Clinical Efficacy of Tiaoganhuazhuo Decoction Combined with Exercise Therapy on MAFLD Based on Magnetic Resonance Imaging
- Conditions
- metabolic associated fatty liver disease
- Registration Number
- ITMCTR2022000065
- Lead Sponsor
- Guang'anmen Hospital,CHINA ACADEMY OF CHINESE MEDICAL SCIENCE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
? Conform to MAFLD's western medicine diagnostic criteria and TCM syndrome diagnostic criteria;
? Aged between 18 and 65;
? Those who have good compliance, are willing to cooperate with the treatment, and sign the informed consent form.
? Pregnant or lactating women; ? Complicated with serious diseases of important organs (such as heart, brain, lung and kidney); ? Patients with infectious hepatitis and liver cirrhosis and liver cancer diagnosed by liver biopsy; Or drug-induced liver disease, genetic factors and other specific diseases that can lead to fatty liver; ? Patients with mental and legal disabilities; ? Suspected or actual history of drug abuse; Alcohol consumption history > 5 years, equivalent to alcohol consumption = 40 g /d for men and = 20 g /d for women; Or have a history of heavy drinking within 2 weeks, equivalent to alcohol volume > 80 g /d; ? Those who are known to be allergic to the components of the drug; ? MRI and exercise contraindications; ? Patients who are participating in other drug clinical trials or who have participated in drug clinical trials within the past month.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method MRI-PDFF;
- Secondary Outcome Measures
Name Time Method iver function test;the waist;glycosylated hemoglobin;Hypersensitive C-reactive protein;TCM symptom score;Blood lipid test;uric acid;routine blood test;Fasting blood glucose;Body mass index;