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Determinants of intra-individual variation of glucoregulation in diabetes mellitus type 1

Conditions
diabetes
glucose metabolism disorders
10018424
Registration Number
NL-OMON32016
Lead Sponsor
eids Universitair Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

• Informed consent
• HbA1c< 8%
• Plasma creatinine levels < 100 µmol/l
• Well regulated blood pressure (i.e. RR < 140/90 mmHg)
BMI 20-25 kg/m2

Exclusion Criteria

• Psychiatric disorders and/or use of antipsychotic or antidepressant drugs at present or in the past
• Use of β-blocking agents, aspirin and prokinetic drugs
• Sleep disorders and/or use of sleep medication
• Renal, hepatic or other endocrine disease
• Any significant chronic disease
• Any significant abnormal laboratory results found during the medical screening procedure
• Pregnancy
• Smoking
• Difficulties to insert an intravenous catheter
• Recent blood donation (within the last 3 months)
• Recent participation in other research projects within the last 3 months or participation in 2 or more projects in one year

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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