Pharmacokinetics of Procaterol in Elite Athletes

Completed

• Conditions: Asthma

• Registration Number: NCT05749536
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

The purpose of the study is to find blood and urine concentrations of procaterol administrated either by inhalation or by tablets in asthmatic and non-asthmatics males. We hypotheis that the concentrations of procaterol in the blood and serum is higher after tablet intake versus inhalation.

Detailed Description

Doping study

Study Timeline

• Study Start: 2011-08
• Primary Completion: 2013-10
• Study Completion: 2013-10
• Study First Submitted: 2013-11-05
• Status Verified: 2023-02
• Study First Submitted QC: 2023-02-27
• Last Update Submitted: 2023-02-27
• Study First Posted: 2023-03-01
• Last Update Posted: 2023-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• Doctor diagnosed asthma for the asthmatic group
• GINA 1-3 for the asthmatic group
• Use of beta2-agonist for at least 12 months for the asthmatic group
• age 18-45
• males
• informed consent

Exclusion Criteria

• smoker or former smoker
• airway infection to weeks prior to the study or during the study
• other chronic diseaes than asthma and allergy
• Use of beta2-agonist 6 days prior to the study
• Allergy to the study medicine

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
urine concentration of drug 0-24 h	7 days	In healthy subjects to investigate drug farmakokenetic
serum concentration of drug 0-24 h	7 days	In healthy subjects to investigate drug farmakokenetic

Trial Locations

Locations (1)

Bispebjerg Hospital; 🇩🇰 Copenhagen, Denmark