Cognitive Function in Adults With Cardiac Disease

University Hospitals Cleveland Medical Center1 个研究点分布在 1 个国家目标入组 66 人开始时间: 2009年7月最近更新: 2022年4月22日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University Hospitals Cleveland Medical Center
入组人数: 66
试验地点: 1
主要终点: Cognitive Function as measured by Modified Mini Mental Status (3MS) Examination

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to identify cardiac patients' degree of unappreciated mild impairment in cognitive function patterns of cognitive function, and influencing factors related to cognitive functioning during hospitalization. The results from the study will contribute to tailoring the delivery of patient education to optimize patient understanding of information in future clinical practice.

It is hypothesized that the study will demonstrate the following:

The degree of cognitive function for patients hospitalized in a CICU will be below the scores for normal functioning adults.
Patients with acute cardiovascular conditions will score differently in cognitive functioning at various times throughout their hospitalization.
Relationships between cognitive function and following variables:

Patients with greater sleep deprivation or fatigue will exhibit lower cognitive functioning.
Patients with greater hunger will exhibit lower cognitive functioning.
Patients who are experiencing greater anxiety will exhibit lower cognitive functioning.
Patients who are experiencing depression will exhibit lower cognitive functioning.
Patients who have undergone or will undergo shortly treatment or procedures will exhibit lower cognitive functioning.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 100 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Admission to the Cardiac Intensive Care Unite for acute cardiological issues during time of enrollment.
•Patients with NYHA class I, II, III, and IV.
•18 years or older and must be awake and conversant at time of enrollment.

排除标准

•History of neurological disorder or injury (e.g., Alzheimer's Disease, dementia, stroke, seizures).
•Moderate or severe head injury (defined as > 24 hours loss of consciousness)
•Past or current history of severe psychiatric illness. Specifically, psychotic disorders (e.g., schizophrenia) and bipolar disorder. Potential participants will not be excluded on the basis of managed depression or anxiety disorder. These conditions are common in cardiac patients and their exclusion may limit the generalizability of findings.
•5 years past or current history of alcohol or drug abuse (defined by DSM-IV criteria).
•History of learning disorder or developmental disability (defined by DSM-IV criteria).
•Renal failure requiring dialysis.
•History of sleep apnea (defined through previous sleep studies).
•Severely ill individuals, including those who are sedated, on a ventilator, exhibiting acute hemodynamic changes, and/or those deemed inappropriate by patient's physician to participate in study.