Cognitive Function in Adults With Cardiac Disease

University Hospitals Cleveland Medical Center1 site in 1 country66 target enrollmentJuly 2009

ConditionsCognitive Impairment Cardiac Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cognitive Impairment
Sponsor: University Hospitals Cleveland Medical Center
Enrollment: 66
Locations: 1
Primary Endpoint: Cognitive Function as measured by Modified Mini Mental Status (3MS) Examination
Status: Completed
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to identify cardiac patients' degree of unappreciated mild impairment in cognitive function patterns of cognitive function, and influencing factors related to cognitive functioning during hospitalization. The results from the study will contribute to tailoring the delivery of patient education to optimize patient understanding of information in future clinical practice.

It is hypothesized that the study will demonstrate the following:

The degree of cognitive function for patients hospitalized in a CICU will be below the scores for normal functioning adults.
Patients with acute cardiovascular conditions will score differently in cognitive functioning at various times throughout their hospitalization.
Relationships between cognitive function and following variables:
- Patients with greater sleep deprivation or fatigue will exhibit lower cognitive functioning.
- Patients with greater hunger will exhibit lower cognitive functioning.
- Patients who are experiencing greater anxiety will exhibit lower cognitive functioning.
- Patients who are experiencing depression will exhibit lower cognitive functioning.
- Patients who have undergone or will undergo shortly treatment or procedures will exhibit lower cognitive functioning.

Registry

clinicaltrials.gov

Start Date

July 2009

End Date

December 2010

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University Hospitals Cleveland Medical Center

Responsible Party

Principal Investigator

Richard Josephson, MS MD

Professor of Medicine

University Hospitals Cleveland Medical Center

Eligibility Criteria

Inclusion Criteria

•Admission to the Cardiac Intensive Care Unite for acute cardiological issues during time of enrollment.
•Patients with NYHA class I, II, III, and IV.
•18 years or older and must be awake and conversant at time of enrollment.

Exclusion Criteria

•History of neurological disorder or injury (e.g., Alzheimer's Disease, dementia, stroke, seizures).
•Moderate or severe head injury (defined as \> 24 hours loss of consciousness)
•Past or current history of severe psychiatric illness. Specifically, psychotic disorders (e.g., schizophrenia) and bipolar disorder. Potential participants will not be excluded on the basis of managed depression or anxiety disorder. These conditions are common in cardiac patients and their exclusion may limit the generalizability of findings.
•5 years past or current history of alcohol or drug abuse (defined by DSM-IV criteria).
•History of learning disorder or developmental disability (defined by DSM-IV criteria).
•Renal failure requiring dialysis.
•History of sleep apnea (defined through previous sleep studies).
•Severely ill individuals, including those who are sedated, on a ventilator, exhibiting acute hemodynamic changes, and/or those deemed inappropriate by patient's physician to participate in study.