Comparison between different nerve blocks for post operative pain relief after Inguinal Hernia Surgeries

Completed

• Conditions: Unilateral inguinal hernia, without obstruction or gangrene,

• Registration Number: CTRI/2019/03/018097
• Lead Sponsor: Dr Anup Gohatre

Brief Summary

Inguinal hernia repair is commonly performed under spinal anesthesia. Inadequate postoperative analgesia is one of the most common causes of poor patient satisfaction. Abdominal field blocks like Transversus Abdominis Plane (TAP) block and Ilioinguinal-Iliohypogastric nerve (II-IH) blocks, because of technical simplicity, opioid-sparing effects, and prolonged pain relief, are the upcoming promising techniques of management of postoperative pain for lower abdominal surgeries.

This randomized prospective study will be carried out on 80 adult patients of ASA physical status I and II, scheduled for elective open inguinal hernia repair surgeries under spinal anesthesia. After the approval by the institutional Ethical Committee, written informed consent will be obtained from all the patients before being included in the study. They will be randomly allocated to following groups of 40 each: Group TAP: Ultrasound-guided TAP block will be given with 20 ml of 0.25% bupivacaine. Group II-IH: Conventional II-IH block will be given with 16 ml of 0.25% bupivacaine.

Time of return of sensation after weaning of spinal anesthesia and time of request of first rescue analgesia will be recorded in all the patients. Amount of i.v. analgesics used in PACU, POD1, POD2. VAS score at rest (VASr) before discharge from PACU, and 4 and 12 h after surgery and VAS score at rest (VASr) as well as on movement (VASm) on the first postoperative day (POD1) and POD2 will be, and 3 and 6 months after surgery will be obtained. LA complication, if any, and urinary retention and leg weakness will be recorded

Detailed Description

Not available

Study Timeline

• Study Start: 2019-03-15
• Study Completion: 2020-06-30
• Last Update Posted: 2022-02-26

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients belonging to American Society of Anesthesiologist (ASA) Grade- I & II, Weighing 40 to 80 Kgs, above 18 years of age, of both the sexes and undergoing elective open inguinal hernia repair surgery under spinal anesthesia.

Exclusion Criteria

Patients not giving consent to the study, Age ≤18 yr BMI ≥40 kg m-2 Skin infection at the puncture site Contraindication to LA agents Chronic hepatic or liver failure Preoperative opioid or non-steroidal anti-inflammatory drugs treatment for chronic pain Patient Refusal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time of request of first rescue analgesia	At 4hrs, 24hrs and 48hrs.
Amount of IV Diclofenac sodium	At 4hrs, 24hrs and 48hrs.
VAS score, at rest, as well as on movement.	At 4hrs, 24hrs and 48hrs.

Secondary Outcome Measures

Name	Time	Method
Complications related with SAB, Urinary retention and leg weakness.	Procedure related complications, such as hematoma, bleeding, loss of sensation and infections.

Trial Locations

Locations (1)

IMS, BHU; 🇮🇳 Varanasi, UTTAR PRADESH, India

IMS, BHU

🇮🇳Varanasi, UTTAR PRADESH, India

Dr Anup Gohatre

Principal investigator

9403173892

anup.gohatre@gmail.com