Comparitive study between two class of anti-hypertensives on intraoperative hemodynamics and surgical conditions during polypectomy surgery

Phase 2/3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/01/039572
• Lead Sponsor: Vinayaka Missions Kirupananda Variayar Medical College and Hospitals

Brief Summary

Functionalendoscopic sinus surgery (FESS) has been a major advancement in the managementof a chronic sinusitis and other sino-nasal diseases.Establishing a nearperfect surgical field during functional endoscopic sinus surgery (FESS) isessential.Minor bleeding can severely compromise an already restricted view obtainedthrough Hopkin’s rigid nasal endoscope.If controlled hypotension can be provided without compromising thesafety of patient by a relatively effortless method, surgical field can beimproved greatly. Hence, we aim to compare the hemodynamic changes and surgicalconditions during FESS following oral premedication with clonidine ormetoprolol in this study.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-12-27
• Study Start: 2022-01-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients undergoing general anaesthesia 2.
• ASA Grading I, II.

Exclusion Criteria

1.ASA 3 and ASA 4 2.Age <18 and >60 years 3.History of hypertension 4.History of asthma 5.Patients already on beta blockers or clonidine 6.Contraindication to general anaesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
estimate the quality of the operative field and to grade according to the Average Category Scale (ACS) proposed by Fromm and Boezaart.	3 hours
Surgical field was graded as	3 hours
Good - ACS 0 or 1	3 hours
Fair - ACS 2 or 3	3 hours
Poor –ACS 4 or 5	3 hours

Secondary Outcome Measures

Name	Time	Method
Blood loss intra operatively	3 hours

Trial Locations

Locations (1)

Vinayaka Missions Kirupananda Variayar Medical College and Hospitals; 🇮🇳 Salem, TAMIL NADU, India

Vinayaka Missions Kirupananda Variayar Medical College and Hospitals

🇮🇳Salem, TAMIL NADU, India

Swadika

Principal investigator

9952348249

swadika3895@gmail.com