Treatment of hypertrophic scars using needle-free jet-injection of triamcinolone and 5-Fluorouracile: a prospective, controlled, randomized, single-blinded split-lesion trial.

Merete Hædersdal0 个研究点目标入组 20 人开始时间: 2019年4月5日最近更新: 2021年6月14日

试验速览

暂无简介。

•Healthy patients above 18 years of age.
•Patients presenting with hypertrophic scar (>4 mm in height)
•The length of scar should be estimated to minimum 3.0 cm or two separate scars with a length of >1cm, with a minimum > 1.0 cm apart in the same body region
•Non-smokers
•Fertile women with negative U-hCG and with use of safe anticontraceptive during the entire study period e.g. oral hormonal contraceptives, intrauterine devices, subdermal implantation or hormonal vaginal ring
•Written informed consent obtained from patient
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 20
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•History of, or presenting with a keloid scar
•If the patient is pregnant or lactating
•use of topical treatment in the last 6 months and lack of willingness to refrain use during the trial as topical treatment, such as i.e. silicone potentially could interfere with the test results
•Anti coagulatory treatment such as Warfarin, Heparin and NOAK.
•Known allergy to the administered medications
•Previous medical treatments of the HTS
•Unable to follow the outlined study protocol

发起方

Merete Hædersdal