Clinical Study to Evaluate the Effect of Shampakadi Niruha Basti in Grahani w.s.r. to Irritable Bowel Syndrome(IBS).

Grahani is having NAMC Code ICD-601 EB-7(1) (disorders of lower Gastro Interstinal tract). Grahani is a chronic gastrointestinal disorder described in Ayurveda under the spectrum of Ashta Mahagada (major diseases) by Acharya Vagbhat. It is primarily a dysfunction of Agni (digestive fire), especially Jatharagni, leading to improper digestion and assimilation of food. The seat of Grahani is considered to be the Grahani organ itself, located anatomically near the Amashaya and Pakvashaya, and physiologically responsible for the retention and release of digested food. According to Acharya Charak, Grahani is a disease which is originated from Mandagni (weak digestion), resulting in the formation of Ama (toxic undigested metabolites), which causes symptoms such as Muhur-Baddha Muhur-Drava, Picchila Mala pravrutti, Aruchi, Asyavairasya, Adhman, Antrakujan, Balakshay and Loha-Amagandhi-Tikta-Amla Udgar(2). It can be correlated with conditions such as irritable bowel syndrome (IBS) in modern medicine. The clinical features of Grahani closely resembles to Irritable Bowel Syndrome (IBS) ICD Code- K 58(1), a functional gastrointestinal disorder marked by abdominal pain or discomfort along with altered bowel habits, despite the absence of any detectable structural abnormalities. Since there are no definitive diagnostic tests for IBS, its diagnosis primarily depends on clinical symptoms by GSRS and IBS Score. IBS is among the most frequently observed conditions in medical practice, yet it remains poorly understood. Globally, approximately 10–20% of adolescents and adults exhibit symptoms consistent with IBS, with a higher incidence reported in females. The severity of symptoms may vary widely, often leading to a considerable decline in quality of life and increased healthcare expenses. Current treatment approaches in modern medicine mostly offer symptomatic relief and may sometimes lead to adverse effects. This creates a promising opportunity for Ayurveda as main line of treatment, to explore more effective and holistic treatment options for IBS. Acharya Sushruta mentioned Shampakadi Basti, a type of Asthapan Basti (decoction-based enema), is mentioned in Ayurvedic texts for its Deepana-Pachana, Vata-Kapha shamaka, and Grahani-hara actions. Niruha Basti is considered one of the most effective therapeutic procedures in Panchakarma for Pakvashaya gata Vata and Grahani disorders.

The Study will be consisting of one Group as per the inclusion criteria that group will receive Yoga Basti Krama using Shampakadi Niruha Basti and Murchita Tila Taila Anuvasana Basti for 8 days.