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Study to Analyze the Efficacy of Chronic Intake With a β-alanine Supplement in Recreational Cyclists

Not Applicable
Completed
Conditions
Beta Alanine Supplementation
Interventions
Other: Control group
Dietary Supplement: Beta Alanine high dose
Dietary Supplement: Beta Alanine low dose
Registration Number
NCT06191055
Lead Sponsor
Universidad Católica San Antonio de Murcia
Brief Summary

Randomized, controlled, double-blind, single-center, controlled clinical trial with three parallel arms depending on the product consumed (experimental product dose 1 and dose 2 and placebo product) to measure the efficacy of 28-day consumption of a sustained-release beta alanine on the physiological efficacy of physical performance in recreational cyclists.

Detailed Description

Subjects meeting the selection criteria will be randomly assigned to each of the study groups (investigational product dose 1 or dose 2, or placebo, depending on the group to which they have been assigned).

The product to be consumed is beta alanine. Participants will consume the product for 28 days. They will have to take 4 intakes every three hours, the first intake being two hours after waking up.

The study subjects will have to make 2 visits to the laboratory. Physical performance and physiological changes will be evaluated with a 10-minute time trial. The first test will be performed without product consumption and the second after 28 days of consumption.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
75
Inclusion Criteria
  • Male cyclists with more than two years of cycling experience.
  • Perform tests without fatigue.
  • Road bike training at least twice a week.
Exclusion Criteria
  • Participants with chronic illness.
  • Have a long-term injury that prevents you from training in the previous month.
  • Inability to understand informed consent.
  • Have consumed beta alanine in the three years prior to the start of the study.
  • Consumption of other supplements that may alter performance.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control groupControl groupConsumption for 28 days.
Beta Alanine high doseBeta Alanine high doseConsumption for 28 days.
Beta Alanine low doseBeta Alanine low doseConsumption for 28 days.
Primary Outcome Measures
NameTimeMethod
PowerIt will be measured on two different occasions. The first day and twenty-eight days later.

Physical performance is measured by direct variables evaluated by the power roller (average power, maximum power, etc.).

Distance coveredIt will be measured on two different occasions. The first day and twenty-eight days later.

Physical performance is measured by direct variables evaluated by the power roller.

Secondary Outcome Measures
NameTimeMethod
FatigueChange of baseline rate of perceived exertion at twenty-eight days

Rate of perceived exertion

Microcapillary bloodIt will be measured on two different occasions. Day one and twenty-eight days later.

This test provides biochemical variables (ABL90FLEX) with 70 ml of capillary blood (Na, K, Glucose, Lactate, etc). It is used to evaluate the effort made by the cyclist.

Body weightThe test will be measured at baseline and after 28 days of consumption.

It is a control variable. Measured by bioimpedance.

Muscle massThe test will be measured at baseline and after 28 days of consumption.

It is a control variable. Measured by bioimpedance.

Fat massThe test will be measured at baseline and after 28 days of consumption.

It is a control variable. Measured by bioimpedance.

Paresthesia testIt will be measured on two different occasions. on day 1 (before consumption) and twenty-eight days after (after consumption).

Visual analogue scale (1-10)

LactateIt will be measured on two different occasions. Day one and twenty-eight days later.

Lactate levels will be measured using the Lactate Pro

Heart RateIt will be measured on two different occasions. Day one and twenty-eight days later.

The heart rate will be evaluated by means of a heart rate strap.

Liver safety variablesIt will be measured twice, once at baseline or at the end of the study after 28 days.

It is a blood test that measures the presence of some enzymes, proteins and bilirubin in the blood, with the aim of determining if there is any alteration in the liver. Enzyme GPT, GOT, Gamma GT, LDH, alkaline phosphatase and bilirubin (UI/L)

Trial Locations

Locations (1)

Catholic University of Murcia

🇪🇸

Murcia, Spain

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