TCTR20220802004已完成2 期
Efficacy of Cannabidiol (CBD) for Treating Recurrent Aphthous Ulcers
Thailand Science Research and Innovation Fund Chulalongkorn University0 个研究点目标入组 69 人开始时间: 2022年8月2日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 69
研究概览
简要总结
The present study demonstrated that CBD reduces ulcer size and accelerates ulcer healing without any local or systemic side effects. CBD exerts an anti-inflammatory effect by reducing the erythematous border size in the early stage and decreases pain intensity in the late stage of RAU. Therefore, CBD may be suitable for RAU patients who desire to avoid the use of steroid medications.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •1. Willing to participate and provide informed consent, 2. Had a history of RAU (at least 2 times/year) on nonkeratinized oral mucosa, 3. Presenting with 1-3 aphthous ulcers (of less than or equal to 48 hours duration) that were 2-10 mm in diameter and easily accessible for evaluation
排除标准
- •1. History of allergies to CBD, 2. Pregnancy/lactation, 3. Concurrent oral bacterial/fungal/viral infections, 4. Ulcers as a manifestation of a systemic disease such as Crohn's disease, Behcet's syndrome, or anemia, 5. Ulcers from trauma, 6. Diabetes mellitus patients, 7. Treatment with systemic steroids, oral retinoids, or other immunomodulatory agents within 1 week, 8. Treatment with nonsteroidal anti-inflammatory drugs, acetaminophen, or oral topical medications within 48 hours or during project participation, 9. History of dental surgery within 2 weeks of entering the study, 10. Orthodontic braces or retainers that might come in contact with the ulcer
研究者
相似试验
尚未招募
Unknown
Effects of cannabidiol (CBD) on muscle recovery and pain in healthy males.ACTRN12624000721505Massey University12
撤回
4 期
CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIFAnkle FracturesTibia FractureNCT04768478NYU Langone Health
Unknown
2 期
Extended Use of Cannabidiol for the Prevention of Graft-versus-host-diseaseGraft vs Host DiseaseNCT02478424Rabin Medical Center10
招募中
3 期
Evaluation of Cannabidiol effect in treatment of patients with Obsessive-Compulsive DisorderObsessive-compulsive disorderIRCT20210310050660N1Qazvin University of Medical Sciences40
已完成
2 期
The Use of Cannabidiol (CBD) in Pain Reduction and Opioid Use After Shoulder ArthroscopyPain, PostoperativeNCT04672252NYU Langone Health100