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Clinical Trials/NCT02362841
NCT02362841CompletedNot Applicable

Assessment of the Evolutions of Transcutaneous CO2 With the Modification of Blood Flow During On-pump Cardiac Surgery

European Georges Pompidou Hospital0 sites41 target enrollmentStarted: January 2012Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
41
Primary Endpoint
PtCO2

Study Overview

Brief Summary

There are no available criteria for determining the optimal flow rate and mean arterial pressure level in patients under cardiopulmonary bypass (CPB). Transcutaneous carbon dioxide tension (PtCO2) has been proposed for microcirculation monitoring and it could be useful for guiding hemodynamic optimization under CPB. The goal of this exploratory study was to determine the factors that influence PtCO2 variations during CPB.

DESIGN: Cutaneous ear lobe CO2 tension was monitored along with hemodynamic parameters every 10 minutes during CPB, until aortic unclamping. SETTING: French university teaching hospital PARTICIPANTS: Patients scheduled for cardiac surgery requiring CPB were prospectively included.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Patients scheduled for cardiac surgery under cardiac arrest and cardiopulmonary bypass were prospectively included in the present observational study conducted at a French teaching hospital.

Exclusion Criteria

  • •The exclusion criteria were: age <18, pregnancy, septic or emergency surgery.

Outcomes

Primary Outcomes

PtCO2

Time Frame: intraoperative value

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
European Georges Pompidou Hospital
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Pirracchio Romain

Dr

European Georges Pompidou Hospital

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