Adrenal Venous Sampling Via an Antecubital Approach
- Conditions
- HyperaldosteronismAngiography
- Registration Number
- NCT03778645
- Lead Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Brief Summary
Currently, adrenal venous sampling (AVS) serves as the gold standard for subtyping of PA. Right adrenal vein catheterization is often difficult due to unfavorable anatomy of the vein including small vein size, short length, caudal direction for the transfemoral approach, and rare drainage to the accessory hepatic vein. All of these factors limit the widespread use of this approach. Given that the right adrenal vein is angled caudally in most patients, AVS via an antecubital approach was performed since January 2012. The purpose of this multicenter retrospective study was to evaluate the safety and feasibility of AVS via the antecubital approach.
- Detailed Description
Primary aldosteronism (PA) is recognized as the most common cause of secondary hypertension, with a prevalence of approximately 10% among unselected hypertensive populations. Subtype diagnosis is crucial because unilateral primary aldosteronism can be treated by laparoscopic adrenalectomy or open surgery, which may result in a cure or significant improvement of blood pressure, thus decreases the incidence of cardio-cerebrovascular complications. Currently, adrenal venous sampling (AVS) serves as the gold standard for subtyping of PA. Given that the right adrenal vein is angled caudally in most patients, AVS via an antecubital approach was performed since January 2012 at the Fuwai Hospital. So far, there have been more than fifteen hospitals to have some experience on AVS via antecubital approach with investigators' helps. The purpose of this multicenter retrospective study was to evaluate the safety and feasibility of AVS via the antecubital approach.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1500
- Consent of the principal investigator to participate to the data collection of patients with primary aldosteronism underwent AVS via antecubital approach
- Refusal of the principal investigator to participate to the AVSA Study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The success rate of bilateral adrenal sampling From January 1st 2012 to December 31st 2018
- Secondary Outcome Measures
Name Time Method The incidence of adrenal vein ruptures occurring during AVS From January 1st 2012 to December 31st 2018 The success rate of right adrenal sampling From January 1st 2012 to December 31st 2018 The success rate of left adrenal sampling From January 1st 2012 to December 31st 2018
Trial Locations
- Locations (10)
Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College
🇨🇳Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University
🇨🇳Chongqing, Chongqing, China
The Second Affiliated Hospital of Nanchang University
🇨🇳Nanchang, Jiangxi, China
The Second Hospital of Dalian Medical University
🇨🇳Dalian, Liaoning, China
Xi'an NO.3 Hospital
🇨🇳Xi'an, Shanxi, China
The Eighth Affiliated Hospital of Sun Yat-sen University
🇨🇳Shenzhen, Guangdong, China
The First Affiliated Hospital of Guangxi Medical University
🇨🇳Nanning, Guangxi, China
Henan Provincial People's Hospital
🇨🇳Zhengzhou, Henan, China
The First Affiliated Hospital of Medical College of Shihezi Universtiy
🇨🇳Shihezi, Xinjiang, China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
🇨🇳Shanghai, Shanghai, China