The Study of Pharmacological Treatment Pattern for Cannabis-induced Psychosis

Completed

• Conditions: Cannabis
• Interventions: Other: cannabis

• Registration Number: NCT04945031
• Lead Sponsor: Mahidol University

Brief Summary

A cross-sectional and retrospective chart review study was conducted at the Princess Mother National Institute on Drug Abuse Treatment (PMNIDAT), Thailand. All patients who admitted at PMNIDAT from October 2013 to September 2019 were included. Patients aged 18-65 years who met the International Classification of Disease-10 (ICD-10) criteria of CIP and Had a positive urine test of cannabis were included. Cannabis use is a component cause of psychosis.More than half of symptoms of cannabis-induced psychosis (CIP) were hallucination, delusion, irritable and anxiety. Antipsychotic drug was still a key psychotropic drugs for treatment of CIP. However, antidepressants and benzodiazepines were commonly used for treatment of other symptoms beyond psychotics

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-08
• Primary Completion: 2020-05-31
• Study Completion: 2020-12-31
• Status Verified: 2021-06
• Study First Submitted: 2021-06-15
• Study First Submitted QC: 2021-06-21
• Last Update Submitted: 2021-06-21
• Study First Posted: 2021-06-30
• Last Update Posted: 2021-06-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 317

Inclusion Criteria

• Patients ≥ 12 years of age
• Patients who had been diagnosed as Cannabis-induced psychosis by International statistical Classification of Disease and Related Health problem (ICD-10) on 2016 code F12.5
• Patients had history of use of cannabis in medical chart
• Patients had the positive urine screening test of cannabis at the first day of admission

Exclusion Criteria

• Patients had psychosis from organic psychosis, defined by diagnosis by ICD-10 code F09.6
• Unavailable data for evaluate of outcome especially data of drug use, content of drug use or urine screening test
• Patients who cancel of medical treatment before 7 day after admission.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cannabis-induced psychosis	cannabis	-

Primary Outcome Measures

Name	Time	Method
Pharmacological treatment pattern for cannabis-induced psychosis	30 days	Pharmacological treatment pattern for cannabis-induced psychosis during admission

Secondary Outcome Measures

Name	Time	Method
Change of Brief psychiatric rating scale (BPRS) form the first day of admission	Day1, Day 8, Day 15 and Day 22	A high BPRS score is more severe of symptoms than a lower score

Trial Locations

Locations (1)

Onrumpha Chuenchom; 🇹🇭 Thanyaburi, Pathum Thani, Thailand