Evaluation of Different Colorectal Cancer Screening Strategies
Not Applicable
- Conditions
- Colorectal Neoplasms
- Registration Number
- NCT05440565
- Lead Sponsor
- Shandong University
- Brief Summary
A large-scale randomized controlled trial was conducted to compare different colorectal neoplasms screening strategies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20000
Inclusion Criteria
- 50-74 years old
- Informed consent is available
Exclusion Criteria
- Previous colorectal cancer
- Previous colorectal resection
- Previous received cancer-related treatment (except non-melanoma skin cancer)
- Colonoscopy, sigmoidoscopy, CT colonoscopy, and barium enema were performed within 5 years
- Fecal occult blood or fecal DNA was performed within one year
- Symptoms of lower digestive tract diseases requiring colonoscopy include: (1) rectal bleeding occurred more than once in the past 6 months, (2) recorded iron deficiency anemia, and (3) recorded significant weight loss within 6 months (> 10% of baseline weight)
- Suffering from other diseases that affect the benefit of screening or intolerance to colonoscopy (for example, severe pulmonary disease, end-stage renal disease, end-stage liver disease, severe heart failure or recently diagnosed cancer, except non-melanoma skin cancer)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Detection rate up to 30 months Detection of intestinal lesions in population
- Secondary Outcome Measures
Name Time Method