ACTRN12617000566336
Completed
未知
A pilot comparative evaluation of the haemodynamic and electrolyte effects of Frusemide and Acetazolamide in critically ill patients
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Kidney disease
- Sponsor
- Austin Health
- Enrollment
- 24
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Admission to the Austin Hospital ICU
- •Age 18 years or greater
- •An attending physician’s decision to administer a diuretic
- •An anticipated ICU length of stay of \>24 hours after frusemide administration
- •Patients with existing intra\-arterial cannulae or central venous catheters for blood sampling, and indwelling urinary catheters.
Exclusion Criteria
- •Patients with known allergy to frusemide or acetazolamide or other sulphonamides.
- •Known existing end stage renal failure
- •Long\-standing use of diuretic therapy
- •Dose of different diuretic in the preceding 12 hours.
- •Significant pre\-existing acid\-base disturbance at time of enrolment (pH \< 7\.30 or \> 7\.50\)
- •Patient receiving continuous renal\-replacement therapy
Outcomes
Primary Outcomes
Not specified
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