Right Versus Left Infraclavicular Approach for Subclavian Vein Cannulation

Not Applicable

Completed

• Conditions: Infraclavicular Vein Cannulation; Venous Cannulation

• Registration Number: NCT06761326
• Lead Sponsor: Alexandria University

Brief Summary

Central venous cannulation is an essential procedure in the anaesthetic and critical care practice. Ultrasound has revolutionized the practice favoring the internal jugular cannulation to the other sites .Subcalvian vein cannulation has fallen out of favor mainly due to the difficult visualization with the ultrasound, especially in obese patients and the inevitable position of the clavicle acting as a bony obstacle , in addition to the anatomical position in vicinity to the pleura which might raise the risk of pneumothorax . Indeed the subclavian vein cannulation is more comfortable and tolerated by the patient especially those requiring long term intravenous therapy, with less rates of infection and thrombosis. This mandated the development of a safer and efficient technique for the cannulation empowered by the ultrasound technology.

The infracalvicular approach or the proximal axillary vein cannulation has been described but is not popular. It provides a potentially safer and successful technique with less complication both in "experienced" and "less experienced"operators . All the patients will receive general anaesthesia with laryngeal mask insertion . Careful sterilization of the surgical site and strict aseptic techniques for the handling of the ultrasound probe will be pursued

Detailed Description

All patients will be in supine position, with the arm abducted to 45 degrees , the angle of the arm will be adjusted to acquire best image. The probe will be placed in he parasagittal plane in the deltopectoral groove medial to the coracoid process . The image will be optimized regarding the depth , focus and the gain accordingly for the best image of the axillary artery and vein similar to that acquired when performing an infraclavicular approach for brachial plexus block . The probe will be rotated to obtain a longitudinal image of the axillary vein . The needle will be introduced in real time imaging , in an in-plane technique and blood will be aspirated , the guidewire will be introduced in real time imaging .The internal jugular vein will be scanned bilaterally via ultrasonography to exclude malposition of the guidewire and will be reported in case of such. The catheter will be introduced through the sheath and will be tunneled the skin, Infraclavicular incision will be performed for the port site , the port will be secured in a dissected pocket right above the pectoralis major muscle .Flush back will be confirmed from the port .The incision will be closed in layers .The final position of the catheter tip will be confirmed using fluoroscopic guidance. In case of difficult visualization or failure of cannulation of one side , the subclavian vein of the contralateral side will be scanned and cannulated . The internal jugular vein will be the cannulated instead if any further difficulties were encountered .

Study Timeline

• Study Start: 2022-10-03
• Primary Completion: 2024-01-21
• Study Completion: 2024-01-21
• Study First Submitted: 2024-10-10
• Status Verified: 2025-01
• Study First Submitted QC: 2025-01-05
• Study First Posted: 2025-01-07
• Last Update Submitted: 2025-02-12
• Last Update Posted: 2025-02-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

.Patients requiring porta Cath insertion.

Exclusion Criteria

.Abnormalities in the platelet count or coagulation .

.Thrombosis of the target vein, .Soft tissue infection of the overlying area.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Incidence of Successful cannulation	Directly after the end of the procedure	Recognition of the catheter in the SVC by fluoroscopy

Secondary Outcome Measures

Name	Time	Method
Rate of malposition identified by the ultrasound	Directly after the insertion of the guidewire and the catheter	The ultrasound probe will be positioned on the internal jugular vein for the recognition of malposition of the guidewire
Complication of the procedures	Directly at the end of the procedure	All the complications will be recognized and reported

Trial Locations

Locations (1)

Medical Research Institute; 🇪🇬 Alexandria, Egypt