Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia

Not Applicable

Completed

• Conditions: Schizophrenia; Mental and Behavioural Disorders

• Registration Number: ISRCTN84216587
• Lead Sponsor: Queen Mary University of London and Barts and the London NHS Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04-07
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 256

Inclusion Criteria

1. Aged between 18 and 65 years, either sex
2. An established diagnoses of schizophrenia according to Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV)
3. Having had symptoms of schizophrenia for at least 6 months
4. Scores of greater than 18 on the subscale negative symptoms of the Positive and Negative Syndrome Scale (PANSS)
5. Willingness to participate in groups for BPT or physical activity (PA)
6. Ability to give written informed consent

Exclusion Criteria

1. Severe physical disability preventing patients from participating in groups for BPT or PA
2. Insufficient command of English so that outcomes cannot be reasonably assessed in English
3. A physical condition that makes participation in either BPT or the PA control group impossible or potentially harmful

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evel of negative symptoms as assessed on the Positive and Negative Symptom Scale of Schizophrenia (PANSS). All outcomes will be measured at pre-treatment baseline, at the end of treatment and again 6 months after treatment.

Secondary Outcome Measures

Name	Time	Method
All outcomes will be measured at pre-treatment baseline, at the end of treatment and again 6 months after treatment:<br>1. Levels of general psychopathology and positive symptoms (PANSS)<br>2. Subjective quality of life (Manchester Short Assessment of Quality of Life)<br>3. Extrapyramidal symptoms (Simpson-Angus Scale)<br>4. Treatment satisfaction (Client Satisfaction Questionnaire)<br>5. Objective social situation (SIX), which combines objective indicators of independent accommodation, employment and having a partner/friend<br>6. Instrumental Activities of Daily Living Scale (IADL)