The use of an iodine 125 marker for perioperative localization in primary hyperparathyroidism, a pilot study.

Completed

• Conditions: parathyroid tumor; primary hyperparathyroidism; 10033949

• Registration Number: NL-OMON36945
• Lead Sponsor: Amphia Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-03-15
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

primary hyperparathyroidism, age >18 year, and a parathyroid adenoma that can be localised by ultrasound in the neck

Exclusion Criteria

age <18 year, secundairy and tertiary hyperparathyroidy and a non visible parathyroid adenoma by ultrasound.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>All data are recorded prospectively. Patient characteristics, indication for<br /><br>surgery (MIP), placement of the I-125 marker (complications, time, difficulty,<br /><br>displacement of the marker), intraoperative data (time to find the marker,<br /><br>blood loss, operative time, use of NIM, occurring of migration, distance to<br /><br>parathyroid / thyroid) and the results of the final pathologic study<br /><br>(diagnosis, radical, effect on parathyroid / thyroid) will be recorded.<br /><br><br /><br>All data will be analyzed and processed in SPSS. It is a prospective study to<br /><br>describe the feasability of I-125 markers in parathryoid surgery.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>