The Physical Exercise and Prostate Cancer Study

Phase 3

Completed

• Conditions: Prostate Cancer
• Interventions: Behavioral: Strength training group

• Registration Number: NCT00658229
• Lead Sponsor: Oslo University Hospital

Brief Summary

The purpose of this study is to determine the effectiveness of a four months strength training program on physical and psychological health in patients with prostate cancer during androgen deprivation therapy. It is hypothesized a beneficial effect of the intervention on physical and psychological health in patients with prostate cancer treated with androgen deprivation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-04-08
• Study First Submitted QC: 2008-04-11
• Study First Posted: 2008-04-14
• Study Start: 2008-11
• Primary Completion: 2012-05
• Study Completion: 2012-05
• Status Verified: 2012-10
• Last Update Submitted: 2012-10-12
• Last Update Posted: 2012-10-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• Newly diagnosed locally advanced prostate cancer (clinical stage T2 and T3)
• Referred to RH and UUS for radiotherapy
• < 75 years
• Capable of reading and writing Norwegian
• Treating oncologist must approve of the subjects' participation
• Living within approximately 1 hour from Oslo by car or public transportation

Exclusion Criteria

• Routinely resistance training with manuals
• Medication for osteoporosis (i.e. bisphosphonates)
• Conditions of a severity that contraindicate exercise without adjusted actions
• Mentally incompetent conditions
• Conditions of a severity that complicates the ability to participate in a supervised training program

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Strength training group	Strength training group	A four months strength training program during androgen deprivation therapy for prostate cancer patietns.

Primary Outcome Measures

Name	Time	Method
lean body mass	before ADT, before and after the intervention

Secondary Outcome Measures

Name	Time	Method
bone mineral density, fat mass, body mass index, serological outcomes (including lipids, hormones and CRP), physical functioning, psycho-social functioning and muscle cellular outcomes (including muscle fiber size and function)	before ADT, before and after the intervention

Trial Locations

Locations (1)

Rikshospitalet- Radiumhospitalet HF; 🇳🇴 Montebello, Oslo, Norway