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Single Crown Supported by Short Implant Versus Standard Implant in Conjunction With Maxillary Sinus Floor Augmentation.

Not Applicable
Active, not recruiting
Conditions
Dental Implant Failed
Interventions
Procedure: 40 patients will be randomly allocated to short implants and standard implants in conjunction with MSFA
Registration Number
NCT04518020
Lead Sponsor
Aalborg University Hospital
Brief Summary

Implant placement in the posterior part of the maxilla is frequently compromised due to atrophy of the alveolar process. Therefore, alveolar ridge augmentation is frequently necessary before or in conjunction with implant placement. The most commonly used method to augment the maxillary premolar and molar region involves the maxillary sinus floor augmentation (MSFA) with autogenous bone graft or a bone substitute. However, the use of autogenous bone grafts is associated with risk at the donor site morbidity and unpredictable graft resorption. Consequently, short implants are used increasingly to eliminate the need for bone augmentation. However, long-term studies comparing short implants and standard implants in conjunction with MSFA supporting single crown restoration in the posterior maxilla are missing. The primary outcome measures include survival of implant and suprastructures, peri-implant marginal bone level (MBL), professional evaluation of the suprastructure and soft tissue using pink esthetic score (PES) and white esthetic score (WES), patient satisfaction using visual analogue scale (VAS), and oral health related quality of life using oral health impact profile (OHIP-14) questionnaire. Secondary outcome measure include evaluation of the complication rate related to the two treatment modalities.

Detailed Description

The primary objective of the present study is to test the H0 hypothesis of:

1. No differences in survival of suprastructures and implants with the two treatment modalities.

2. No differences in peri-implant MBL, PES, WES, and patient satisfaction using VAS with the two treat modalities.

3. No differences in oral health related quality of life using OHIP-14 with the two treatment modalities.

The secondary objective will include:

1. Complications related to bone harvesting, implant installation, and MSFA.

The primary outcome measures included:

* Survival of suprastructures.

* Survival of implants.

* Radiographic peri-implant MBL.

* Professional evaluation of suprastructure and soft tissue using PES and WES.

* Patient satisfaction using VAS

* Oral health related quality of life using OHIP-14 questionnaire.

Secondary outcome measures:

• Pre- and postoperative complications.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
40
Inclusion Criteria
  • >20 years
  • Partial edentulism in the posterior maxilla.
  • Height and weight of the maxillary alveolar process of at least 5.5 mm.
  • Mandibular occluding teeth.
Exclusion Criteria
  • General contraindications to implant therapy.
  • Poor oral hygiene.
  • Progressive periodontitis.
  • Acute infection in the area intended for implant placement.
  • Parafunction, bruxism, or clenching.
  • Psychiatric problems or unrealistic expectations.
  • Heavy tobacco use, define as >10 cigarettes per day.
  • Pregnancy

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Short implant40 patients will be randomly allocated to short implants and standard implants in conjunction with MSFAShort implant 6 mm installed
Conventional implant + bone augmentation40 patients will be randomly allocated to short implants and standard implants in conjunction with MSFAStandard length implant 13 mm in conjunction with maxillary sinus floor augmentation serves as a control group
Primary Outcome Measures
NameTimeMethod
Oral health related quality of life as defined by oral health impact profile (OHIP-14).1-year follow up

Evaluation of oral health related quality of life using OHIP-14 questionnaire. OHIP-14 scale ranges from 0 to 56, with higher scores indicating poorer oral health impact profile.

Professional evaluation of the prosthetic restoration and soft tissue using pink esthetic score (PES) and white esthetic score (WES).1-year follow up

Esthetic evaluation of suprastructure and soft tissue using PES and WES. PES includes 7 different variables: mesial papilla, distal papilla, soft-tissue level, soft-tissue contour, alveolar process deficiency, soft-tissue colour, and texture. Each variable is assessed with a 0, 1, or 2 score, with 0 being the poorest score and 2 the best according to the degree of match or mismatch compared with the anterior premolar or molar. The highest possible PES is 14. WES includes 5 different variables: Crown form, volume, colour, translucency, and texture. Each variable is assessed with a 0, 1, or 2 score, with 0 being the poorest score and 2 the best according to the degree of match or mismatch compared with the anterior premolar or molar. The highest possible WES is 10.

Survival of suprastructures.1-year follow up

Survival of suprastructures is defined as absence of mechanical/or biological complications causing loss of suprastructures. Chipping of ceramics and loosening of the suprastructure were not categorized as loss of suprastructure.

Survival of implants.1-year follow up

Survival of implants is defined as clinically stable and osseointegrated implants with absence of mobility, progressive marginal bone loss, and infection.

Radiographic MBL.1-year follow up

Measurement of marginal bone level in millimeter.

Patient satisfaction.1-year follow up

Evaluation of patient satisfaction using visual analogue scale (VAS). VAS with 0 indicating extreme dissatisfaction and 10 indicating complete satisfaction.

Secondary Outcome Measures
NameTimeMethod
Complications.1-year follow up

Evaluation of biological and mechanical complication rate.

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