NCT02620891已完成不适用
Study on the Effect of Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome Parallel Synchronized Intermittent Mandatory Ventilation; Synchronous Maudatory Ventilation
Ma Juan1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2015年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- blood gas analysis
研究概览
简要总结
Helium-oxygen mixture(heliox) was suggested to be beneficial in meconium aspiration syndrome in previous studies，but the evidence was limited．The aim of the study was to assess the effectiveness of synchronize intermittent mandatory ventilation (SIMV) with heliox (70% helium and 30% oxygen) on length of ventilation(LoV) and cardiopulmonary protection in meconium aspiration syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 37 Weeks 至 40 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subject has the diagnosis of neonatal meconium aspiration syndrome
- •Subject has Synchronous instruction ventilation
排除标准
- •History of congenital or hereditary disease
结局指标
主要结局
blood gas analysis
时间窗: 48 hour
次要结局
- Inflammatory response index (IL-6,IL-8, TNF-a,CRP)(6 hour)
研究者
Ma Juan
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
研究点 (1)
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