Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone
Overview
- Phase
- Phase 2
- Status
- Recruiting
- Sponsor
- Beni-Suef University
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- Remaining width of the attached gingiva
Overview
Brief Summary
Gingival Pyogenic granuloma in the esthetic zone represents an esthetic problem. While surgical treatment may not give the premium esthetic demands, corticosteroid may acheive this balance.
Detailed Description
In our practice, the investigators have found the use of topical steroids effectively induced regression of PGs. This protocol has been suggested by published case reports supported by the anti-inflammatory actions corticosteroid.
This is a particularly valuable approach for patients who have PG in the esthetic zone allowing the surgeon to keep maximum amount of periodontal tissues.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients with oral pyogenic granuloma at the esthetic zone
Exclusion Criteria
- •Patients who were not compliant to oral hygiene instructions and can not be motivated
Arms & Interventions
Control arm
Surgical excision of the gingival pyogenic granuloma
Intervention: Solu-Cortef (Drug)
Intervention
Intralesional injection with corticosteroids solution (1.8 mL of 100 mg hydrocortisone)
Intervention: Solu-Cortef (Drug)
Outcomes
Primary Outcomes
Remaining width of the attached gingiva
Time Frame: 6 month
Remaining width of the attached gingival it is measured using graduated probe
Secondary Outcomes
- Recurrence of the lesion(6 months)
Investigators
Eman Magdy Ahmed
Principal Investigator
Beni-Suef University