De FOCOM studie: een studie naar activatie van hersengebieden tijdens het maken van opdrachten op de computer
Completed
- Conditions
- aging - verouderingworking memory - werkgeheugenresponse inhibition - respose inhibitie
- Registration Number
- NL-OMON25944
- Lead Sponsor
- Wageningen University, division of Human Nutrition
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Males and females aged 18-35 years (young adults group)
- Males and females aged 60-75 years (older adults group)
Exclusion Criteria
- Mini-Mental State Examination (MMSE) score ¡Ü 26 (older subjects group)
- Estimated IQ < 85 (based on Nederlandse Leestest voor Volwassenen [NLV]-score)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oxygenated (O2Hb) and deoxygenated (HHb) hemoglobin concentration changes (ìmol/L), measured during baseline and the performance of the cognitive paradigm
- Secondary Outcome Measures
Name Time Method - Total hemoglobin changes (O2Hb + HHb) (ìmol/L), measured during baseline and the performance of the cognitive paradigm<br /><br>- EEG frequency bands measured during baseline and the performance of the cognitive paradigm<br /><br>- Blood pressure (mmHg), measured during baseline and the performance of the cognitive paradigm<br /><br>- Heart rate (bpm), measured during baseline and the performance of the cognitive paradigm<br /><br>- Exhaled CO2 (%), measured during baseline and the performance of the cognitive paradigm<br /><br>- Performance on the cognitive tasks<br /><br>- Hospital Anxiety and Depression Scale (HADS)<br /><br>- Short Questionnaire to Assess Health enhancing physical activity (SQUASH)<br /><br>- Barratt Impulsiveness Scale (BIS-11)<br /><br>- Cognitive Failure Questionnaire (CFQ) (only older adults group)<br /><br>- Performance on the additional neuropsychological test battery