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Clinical Trials/NCT06300710
NCT06300710
Not yet recruiting
Not Applicable

Outcome of Cardiopulmonary Resuscitation in Tertiary Level PICU and Associated Risk Factors

Assiut University0 sites30 target enrollmentAugust 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardio Respiratory Arrest
Sponsor
Assiut University
Enrollment
30
Primary Endpoint
incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

  1. To detect the frequency and the underlying causes of cardiopulmonary arrest .
  2. To detect outcome of CPR
  3. To identify the associated risk factors for the different outcomes after CPR among those patients

Detailed Description

Cardiac arrest (CA) is uncommon in children, and the epidemiology of pediatric CA is different from adults. CA Is a critical cause of death in children in the hospital especially in the pediatric Intensive care unit (PICU). CA Is reported in 2-6% of children in the PICU, which is much higher than out-of-hospital arrest (about 8 to 20 annual cases per 100,000 pediatric population . Previous studies reported that return of spontaneous circulation (ROSC) after cardiopulmonary Resuscitation (CPR) for in-hospital CA (IHCA) is about half of these patients, and ∼30% survived to hospital discharge Previous studies had analyzed the cause and prognostic factors associated with outcomes after IHCA, which included the Initial rhythm, duration of CA and CPR, the underlying disease, and where the event attacked . Patients in PICU are more likely to develop CA because they are more critically ill. Information on factors associated with prognosis of in-PICU CA can promote Improvement in PICU care, which means improving survival with good neurologic outcomes . Analyzing the epidemiological variables and risk/prognostic factors of in-PICU CA is of great Importance in developing the better therapeutic strategy and deciding appropriate preventive Measure . Probability of death on admission and a longer length Of stay in the PICU were associated with increased odds of receiving CPR. Children admitted with cardiac conditions were at significantly higher risk of receiving CPR in the PICU Compared with those Admitted with noncardiac primary diagnosis. The risk Of receiving CPR was significantly associated with age, History of preadmission CPR, also, Electrolyte Imbalances and Multi-organ Dysfunction increase risk of receiving CPR in PICU .

Registry
clinicaltrials.gov
Start Date
August 1, 2024
End Date
March 1, 2025
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Eman Hamed Khalaf Ahmed

Principal investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Including Children aged 1 month to 18 years who received at least 1 minute of CPR

Exclusion Criteria

  • Exclusion of 1-Children aged below1 month and older than 18 years .
  • terminal disease patients, such as malignancy

Outcomes

Primary Outcomes

incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)

Time Frame: 1 year

(dead versus alive)

Secondary Outcomes

  • Rate of risk factors associated with outcome of CPR(1 year)

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