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临床试验/NCT06300710
NCT06300710尚未招募不适用

Outcome of Cardiopulmonary Resuscitation in Tertiary Level PICU and Associated Risk Factors

Assiut University0 个研究点目标入组 30 人开始时间: 2024年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
主要终点
incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)

研究概览

简要总结

  1. To detect the frequency and the underlying causes of cardiopulmonary arrest .
  2. To detect outcome of CPR
  3. To identify the associated risk factors for the different outcomes after CPR among those patients

详细描述

Cardiac arrest (CA) is uncommon in children, and the epidemiology of pediatric CA is different from adults. CA Is a critical cause of death in children in the hospital especially in the pediatric Intensive care unit (PICU). CA Is reported in 2-6% of children in the PICU, which is much higher than out-of-hospital arrest (about 8 to 20 annual cases per 100,000 pediatric population .

Previous studies reported that return of spontaneous circulation (ROSC) after cardiopulmonary Resuscitation (CPR) for in-hospital CA (IHCA) is about half of these patients, and ∼30% survived to hospital discharge Previous studies had analyzed the cause and prognostic factors associated with outcomes after IHCA, which included the Initial rhythm, duration of CA and CPR, the underlying disease, and where the event attacked .

Patients in PICU are more likely to develop CA because they are more critically ill. Information on factors associated with prognosis of in-PICU CA can promote Improvement in PICU care, which means improving survival with good neurologic outcomes .

Analyzing the epidemiological variables and risk/prognostic factors of in-PICU CA is of great Importance in developing the better therapeutic strategy and deciding appropriate preventive Measure .

Probability of death on admission and a longer length Of stay in the PICU were associated with increased odds of receiving CPR. Children admitted with cardiac conditions were at significantly higher risk of receiving CPR in the PICU Compared with those Admitted with noncardiac primary diagnosis. The risk Of receiving CPR was significantly associated with age, History of preadmission CPR, also, Electrolyte Imbalances and Multi-organ Dysfunction increase risk of receiving CPR in PICU .

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
1 Month 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Including Children aged 1 month to 18 years who received at least 1 minute of CPR

排除标准

  • Exclusion of 1-Children aged below1 month and older than 18 years .
  • terminal disease patients, such as malignancy

结局指标

主要结局

incidence of cardiac arrest and survival to discharge from the PICU (dead versus alive)

时间窗: 1 year

(dead versus alive)

次要结局

  • Rate of risk factors associated with outcome of CPR(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Eman Hamed Khalaf Ahmed

Principal investigator

Assiut University

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