Association Between Mortality and Diabetes in Elderly Koreans: the South-West Seoul (SWS) Study

Completed

• Conditions: Apparently Healthy Elderly People; (Between 60-92 Years of Age)

• Registration Number: NCT01977391
• Lead Sponsor: Korea University

Brief Summary

Diabetes mellitus is known to increase the risk of premature death in the general population. In this study, the investigators examine the impact of body mass index (BMI) levels, waist circumference, and presence/absence of diabetes on all-cause and cardiovascular mortality in elderly Koreans.

Detailed Description

The investigators analyze follow-up data from the South-West Seoul (SWS) Study, a prospective observational cohort study of an elderly Korean population residing in Seoul, the metropolitan capital city of Korea.

Briefly, the study population was selected from four urban districts (Guro, Yangcheon, Gwanak and Gangseo) located in the south-west area of Seoul. A total of 1737 apparently healthy individuals (between 60 and 92 years of age) eventually participated in this survey starting in 1999. A follow-up examination was performed in 2002, and an additional 873 subjects who had not participated in the first examination were newly recruited.

After a median follow-up of 10 years, each subject's vital status or cause of death as of 31 December 2011 was determined after linking these cohort data with death certificate data from the Korean National Statistical Office. Terminology and codes from the International Classification of Disease, Tenth Revision (ICD-10), were used to classify the underlying cause of death due to cardiovascular disease (ICD-10 codes I00-I79), cancer (ICD-10 codes C00-C97) and others.

Study Timeline

• Study Start: 1999-08
• Primary Completion: 2002-12
• Study Completion: 2011-12
• Study First Submitted: 2013-10-30
• Study First Submitted QC: 2013-10-30
• Status Verified: 2013-11
• Study First Posted: 2013-11-06
• Last Update Submitted: 2013-11-06
• Last Update Posted: 2013-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2263

Inclusion Criteria

• Apparently healthy individuals
• Over the age of 60 years

Exclusion Criteria

• Those with a mismatched identification number
• Missing data regarding BMI, waist circumference, and presence of diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause and cardiovascular mortality in elderly Korean men and women according to BMI, waist circumference, and presence of diabetes	A median follow-up of 10 years

Secondary Outcome Measures

Name	Time	Method
Survival probability among study populations	A median follow-up of 10 years

Trial Locations

Locations (1)

Korea Univ. Guro Hospital; 🇰🇷 Seoul, Korea, Republic of