Prediction Model of Acute Postoperative Pain in Bilateral Total Knee Replacement Arthroplasty Patient: Multivariable Model Including "Surgical History Within 2 Weeks" as a Predictive Factor
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Consumption of analgesics
Study Overview
Brief Summary
This study aims to predict risk factors of acute postoperative pain of the patients undergoing Total Knee Replacement Arthroplasty(TKRA).
Detailed Description
Patients undergoing bilateral TKRA are recruited. The time interval between the surgery of each leg is within 2 weeks. Before each surgery, patients will be asked to conduct questionnaires of Hospital Anxiety and Depression Scale(HADS) and Pain Catastrophizing Scale(PCS). In addition, the patients will have their preoperative knee pain(measured by Knee injury and Osteoarthritis Outcome Score), preoperative pain in other sites, expectation of postoperative pain(measured by Numerical Rating Scale), and morbidity of diabetic neuropathy recorded. Demographic factors including age, sex, and BMI of patients will be collected. Twenty four and forty eight hours after completion of the surgery, each patient will be asked to report thier acute postoperative pain on Numerical Rating Scale.
This study aims to find out risk factors of acute postoperative pain, including identical surgical history within 2 weeks, in patients undergoing bilateral TKRA.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 79 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients undergoing bilateral TKRA with spinal anesthesia
- •patients who have their second TKRA in one leg within 2 weeks after their first TKRA in the other leg.
- •patients who are classified to the state of ASA physical status classification system Ⅰ,Ⅱ, or Ⅲ.
Exclusion Criteria
- •patients incapable of communication
Outcomes
Primary Outcomes
Consumption of analgesics
Time Frame: 48 hours
Cumulative consumption of Patient-Controlled Analgesia(PCA) and rescue analgesics is recorded.
Acute post operative pain
Time Frame: 48 hours
Acute post operative pain is recorded on NRS(a pain scale ranging from 0 to 10. the higher number means the higher pain) at rest in an attempt to bent knee.
Secondary Outcomes
- Preoperative anxiety and depression(one day before the surgery: 20 hours before the surgery)
- Diabetic neuropathy(one day before the surgery: 20 hours before the surgery)
- Pain expectation of acute postoperative pain(one day before the surgery: 20 hours before the surgery)
- Pain catastrophizing level(one day before the surgery: 20 hours before the surgery)
- Preoperative knee pain(one day before the surgery: 20 hours before the surgery)
- Demographic data(one day before the surgery: 20 hours before the surgery)
- Preoperative pain in other sites(one day before the surgery: 20 hours before the surgery)
Investigators
Jin-Tae Kim
Professor
Seoul National University Hospital