Clinical Effects of Large Segmental Bone Defects With 3D Printed Titanium Implant
Not Applicable
- Conditions
- Large Segmental Bone Defect
- Interventions
- Device: 3D printed titanium implant
- Registration Number
- NCT03941028
- Lead Sponsor
- Peking University Third Hospital
- Brief Summary
The investigators apply 3D printed titanium implant to treat bone defects. Without using bone grafts and growth factors, the investigators anticipate the titanium implant alone can help bone reconstruction.
- Detailed Description
The investigators treat large segmental bone defects caused by three reasons, including trauma, infection and tumor. In this study, polyporous 3D printed titanium implant is applied to reconstruct the bone defects and the investigators will follow up patients' function and bone regeneration.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- bone defects caused by trauma or infection or tumor
- the length of bone defect is more than 6cm
- more than 18 years old
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Exclusion Criteria
- malignant tumor
- patients with bad conditions failing to tolerate surgery
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description bone defects caused by infection 3D printed titanium implant Large bone defects caused by chronic osteomyelitis bone defects caused by tumor 3D printed titanium implant Large bone defects caused by benign tumor bone defects caused by trauma 3D printed titanium implant Large bone defects (\>6cm) caused by trauma
- Primary Outcome Measures
Name Time Method Bone reconstruction 1 year X-rays and CT scans are used to evaluate the bone reconstruction
- Secondary Outcome Measures
Name Time Method Questionnaire of limb function 1 year Restoration of limb function.
Trial Locations
- Locations (1)
Peking University Third Hospital
🇨🇳Beijing, Beijing, China