In adult patients with acute organophosphorus pesticides poisoning could the use of N-acetylcysteine besides the standard treatment compared to the use of the standard treatment alone reduce mortality?

Dr. Ahmad El-Ebiary0 个研究点目标入组 30 人开始时间: 2014年4月15日最近更新: 2020年1月13日

适应症

试验速览

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•Patients (male or female, aged 18 years or older) with symptomatic acute OP poisoning (deliberate or accidental), with diagnosis made on the basis of the typical clinical toxidrome of cholinergic and nicotinic manifestations due to and following shortly after a single exposure to OP, besides reliable identification of the compound based on the container brought by patient attendants or a subsequent confirmation by pseudocholinesterase.

•- Patients who do not consent
•- Patients less than 18 years of age
•- Pregnant and lactating women
•- Patients with ingestion or exposure to other substances in addition to the OP
•- Patients with other major medical conditions (e.g. cardiovascular disease, renal or hepatic failure)
•- Patients presenting more than 12 hours of having consumed the OP compound (late presenters)

发起方

Dr. Ahmad El-Ebiary