se of acetylcysteine as an adjuvant treatment for patients with acute organophosphorus pesticides poisoning

• Conditions: acute organophosphorus pesticides poisoning; Injuries and Accidents - Poisoning

• Registration Number: ACTRN12614000407695
• Lead Sponsor: Dr. Ahmad El-Ebiary

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients (male or female, aged 18 years or older) with symptomatic acute OP poisoning (deliberate or accidental), with diagnosis made on the basis of the typical clinical toxidrome of cholinergic and nicotinic manifestations due to and following shortly after a single exposure to OP, besides reliable identification of the compound based on the container brought by patient attendants or a subsequent confirmation by pseudocholinesterase.

Exclusion Criteria

- Patients who do not consent
- Patients less than 18 years of age
- Pregnant and lactating women
- Patients with ingestion or exposure to other substances in addition to the OP
- Patients with other major medical conditions (e.g. cardiovascular disease, renal or hepatic failure)
- Patients presenting more than 12 hours of having consumed the OP compound (late presenters)

Study & Design

• Study Type: Interventional
• Study Design: Not specified