sedative effect of propofol and ketofol on patients undergoingcoronary artery bypass graft (CABG)

Phase 1

Conditions: Ischaemic heart diseases.
Ischaemic heart diseases
E120,E121,

Registration Number: IRCT201510314583N7

Lead Sponsor: Vice chancellor of Shahid Sadoughi university of medical sciences.

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 45

Inclusion Criteria

patients 40-60 years old with ASA 1,2 undergoing CABG in ICU in Afshar Hospital

Exclusion criteria: patients requiring inotropic drugs; patients with impaired renal tests; addicted patients ; ejection fraction <40%; patients requiring hospitalization in the ICU for more than 24 hours; patients with known psychiatric problems; patients with history of seizure

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: each two hours after the beginning of the process. Method of measurement: according to Behavioral Pain Scale (Questionnaire).;Heart rate. Timepoint: every 30 minutes at the first four hours and then each one hour after that until extubation. Method of measurement: by monitoring.;Systolic blood pressure. Timepoint: every 30 minutes at the first four hours and then each one hour after that until extubation. Method of measurement: by monitoring.;Diastolic blood pressure. Timepoint: every 30 minutes at the first four hours and then each one hour after that until extubation. Method of measurement: by monitoring.;Mean arterial blood pressure. Timepoint: every 30 minutes at the first four hours and then each one hour after that until extubation. Method of measurement: by monitoring.;Patient sedation. Timepoint: once. Method of measurement: by Richmond scale (Questionnaire).

Secondary Outcome Measures