Central Meditation and Imagery Therapy for Augmentation of Borderline Personality Disorder Treatment

Not Applicable

Completed

• Conditions: Borderline Personality Disorder
• Interventions: Behavioral: Central Meditation and Imagery Therapy

• Registration Number: NCT02125942
• Lead Sponsor: University of California, San Francisco

Brief Summary

Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice.

The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial.

During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-04
• Study First Submitted: 2014-04-26
• Study First Submitted QC: 2014-04-26
• Study First Posted: 2014-04-29
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-11
• Last Update Posted: 2021-01-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Meeting the diagnostic criteria for BPD according to DSM-IV criteria
• Meeting the diagnostic criteria for BPD based on the Diagnostic Interview for Borderline - Revised
• Currently receiving psychotherapy.
• English language proficiency to understand written and oral communication

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Exclusion Criteria

• Active suicidality or suicidal intent as identified on the Columbia Suicide Severity Rating Scale
• Suicide attempt within the past month

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
meditation	Central Meditation and Imagery Therapy	Central Meditation and Imagery Therapy

Primary Outcome Measures

Name	Time	Method
Borderline Symptoms	6 weeks	Borderline Symptom List

Secondary Outcome Measures

Name	Time	Method
Depression	6 weeks	Quick Inventory of Depressive Symptoms
Positive Affect	6 weeks	Positive and Negative Affect Scale
Anxiety	6 weeks	Trait Anxiety Inventory

Trial Locations

Locations (1)

University of California, Los Angeles; 🇺🇸 Los Angeles, California, United States